R. Goodrum, R. Aggarwal, H. Li. Gold-nanoparticle-embedded membrane (GEM) for highly sensitive multiplexed sandwich immunoassays. Sensors and Actuators B: Chemical. Accepted, 2024.
S. Durairaj, D. Sridhar, G. Strohle, H. Li, A. Chen. Bactericidal effect and cytotoxicity of graphene oxide/silver nanocomposites. ACS Applied Materials & Interfaces. Accepted, 2024.
R. Goodrum, H. Li. Advances in 3D metal enhanced fluorescence based biosensors using metal nanomaterial and nano-patterned surfaces. Biotechnology Journal. 19:2300519, 2024.
S. Lepard, I. Spotts, C. H. Brodie, C. A. Leclerc, R. Eswar, H. Li, C. M. Collier. A digital microfluidic chip with programmable open system actuation and enhanced optical annealing with near-infrared light. Engineering Reports. 6, e12737, 2024.
R. Goodrum, H. Weldekidan, H. Li, A. K. Mohanty, M. Misra. Graphene-based nanostructures from green processes and their applications in biomedical sensors. Advanced Industrial and Engineering Polymer Research. 7, 37-53, 2024.
D. Sebben, H. Li. Intracellular metal enhanced fluorescence utilizing gold nanoparticles embedded in hydrogel droplets for sensitive protein detection in cells. Talanta Open. 8, 100265, 2023.
R. Aggarwal, L. Lai, H. Li. Microarray fabrication techniques for multiplexed bioassay applications. Analytical Biochemistry. 683, 115369, 2023.
H. Li. Engineering highly sensitive multiplexed biochips. CSME Bulletin, Faculty Spotlight, 2023.
R. Aggarwal, B. Ferris, H. Li. Compartmentalized linker array: a scalable and transferrable microarray format for multiplexed immunoassays. Analytical Chemistry. 95, 9068-9075, 2023.
D. Sebben, G. Strohle, P. Roy, H. Li. Gold-nanoparticle-embedded hydrogel droplets with enhanced fluorescence for imaging and quantification of proteins in cells. Microchimica Acta. 190, 144, 2023.
G. Strohle, H. Li. Comparison of blocking reagents for antibody microarray-based immunoassays on glass and paper membrane substrates. Analytical and Bioanalytical Chemistry. 415, 1967-1977, 2023.
J. Zhang, H. Li. Identification of potential extracellular vesicle protein markers altered in osteosarcoma from public databases. Proteomics Clinical Applications. 17, 4, 2200084, 2023.
G. Strohle, J. Gan, H. Li. Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis. Analytical and Bioanalytical Chemistry. 414, 7051-7067, 2022.
N. Momenbeitollahi, R. Aggarwal, G. Strohle, A. Bouriayee, H. Li. Extracellular vesicle (EV) dot blotting for multiplexed EV protein detection in complex biofluids. Analytical Chemistry. 94, 20, 7368–7374, 2022.
N. Momenbeitollahi, J. van der Zalm, A. Chen, H. Li. Methods for enhanced fluorescence detection of proteins by using entrapped gold nanoparticles in membranes. Current Protocols. 2(3):e404, 2022.
N. Momenbeitollahi, J. van der Zalm, A. Chen, H. Li. Entrapping gold nanoparticles in membranes for simple-to-use enhanced fluorescence detection of proteins. Analytica Chimica Acta. 1195, 339443, 2022.
L. Chin, H. Li, J. Choi, Y. Iwamoto, J. Oh, J. Min, S. Beak, D. Yoo, C. Castro, D. Lee, H. Im. Hydrogel stamping for rapid, multiplexed, point-of-care immunostaining of cells and tissues. ACS Applied Materials & Interfaces. 24, 27613–27622, 2022.
G. Chatterjee, B. Ferris, N. Momenbeitollahi, H. Li. In-silico selection of cancer blood plasma proteins by integrating genomic and proteomic databases. Proteomics. 22, 2022.
N. Momenbeitollahi, T. Cloet, H. Li. Pushing the detection limits: strategies towards highly sensitive optical-based protein detection. Analytical and Bioanalytical Chemistry. 413, 5995-6011, 2021.
J. Park, J. Park, C. Huang, A.Jo, K. Cook, R. Wang, H.Lin, J. Deun, H. Li, J. Min, L. Wang, G.Yoon, B. Carter, L. Balaj, G. Choi, C. Castro, R. Weissleder, H. Lee. An integrated magneto-electrochemical device for the rapid profiling of tumor extracellular vesicles from blood plasma. Nature Biomedical Engineering. 5, 678-689. 2021.
T. Cloet, N. Momenbeitollahi, H. Li. Recent advances on protein-based quantification of extracellular vesicles. Analytical Biochemistry. 622, 114168, 2021.
J. V. Deun, A. Jo, H. Li, H. Lin, R. Weissleder, H. Im, H. Lee. Integrated dual-mode chromatography to enrich extracellular vesicles from plasma. Advanced Biosystems. 12, 2020.
R. Popp, H. Li, C. Borchers. Immuno-MALDI (iMALDI) mass spectrometry for the analysis of proteins in signalling-pathways. Expert Review of Proteomics. 15, 701-708, 2018.
H. Li, G. Brewer, G. Ongo, F. Normandeau, A. Omeroglu, D. Juncker. Immunohistochemistry microarrays. Analytical Chemistry, 89, 8620-8625, 2017. (Featured in 360 DX published by GenomeWeb LLC)
H. Li, R. Popp, C. Borchers. Affinity-mass spectrometric technologies for quantitative proteomics in biological samples. Trends in Analytical Chemistry, 90, 80-88, 2017. (Cover Image for Journal)
R. Popp, H. Li, Y. Mohammed, A. Aguilar-Mahecha, A. Chambers, C. Lan, O. Potz, M. Basik, G. Batist, C. Borchers. Immuno-Matrix-Assisted Laser Desorption/Ionization assays for quantifying AKT1 and AKT2 in breast and colorectal cancer cell lines and tumors. Analytical Chemistry, 89, 10592-10600.
H. Li, R. Popp, D. Juncker, C. Borchers. Bead-Extractor Assisted Ready-to-use reagent System (BEARS) for immunoprecipitation coupled to MALDI-MS. Analytical Chemistry, 89, 3834-3839, 2017.
H. Li, S. Bergeron, D. Juncker. Snap chip for cross-reactivity-free and spotter-free multiplexed sandwich immunoassays. Journal of Visualized Experiments, 129, 2017.
R D. Pedde, H. Li, C. Borchers, M. Akbari. Microfluidic-mass spectrometry interfaces for translational proteomics. Trends in Biotechnology, 35, 954-970, 2017.
H. Li, J. Han, J. Pan, T. Liu, C. Parker, C. Borchers. Current trends in quantitative proteomics – an update. Journal of Mass Spectrometry, 52, 319-341, 2017. (Featured Article and Cover Image for Journal)
H. Li, R. Popp, B. Frohlich, M. Chen, C. Borchers. Protein quantification using automated immuno-MALDI (iMALDI). Journal of Visualized Experiments, 126, e55933, 2017.
H. Li, J. Munzar, A. Ng, D. Juncker. A versatile snap chip for high-density sub-nanoliter chip-to-chip reagent transfer. Scientific Reports 5, 11688, 2015.
S. Bergeron, V. Laforte, P. Lo, H.Li, D. Juncker. Evaluating mixtures of 14 hygroscopic additives to improve antibody microarray performance. Analytical and Bioanalytical Chemistry, 407, 8451-8462, 2015.
H. Li, S. Bergeron, M. Annis, P. Siegel, D. Juncker. Serial analysis of 38 proteins during the progression of human breast tumor in mice using an antibody colocalization microarray. Molecular & Cellular Proteomics M114.046516, 2015.
D. Juncker, S. Bergeron, V. Laforte, H. Li. Cross-reactivity in antibody microarrays and multiplexed sandwich assays: shedding light on the dark side of multiplexing. Current Opinion In Chemical Biology 18, 29037, 2014.
H. Li, S. Bergeron, D. Juncker. Microarray-to-microarray transfer of reagents by snapping of two chips for cross-reactivity-free multiplex immunoassays. Analytical Chemistry 84, 4776-4783, 2012. (Featured in Chemical & Engineering News)
H. Li, R.F. Leulmi, D. Juncker. Hydrogel droplet microarrays with trapped antibody-functionalized beads for multiplexed protein analysis. Lab on a Chip 11, 528-534, 2011. (Ranked as the 3rd most accessed article in December 2010 from the online version of Lab on a Chip)
M. Mirzaei, M. Pla-Roca, R. Safavieh, E. Nazarova, M. Safavieh, H. Li, J. Vogel, D. Juncker. Microfluidic perfusion system for culturing and imaging yeast cell microarrays and rapidly exchanging media. Lab on a Chip 10, 2449-2457, 2010.